Friday, June 27, 2014
"I know that love gives you more than what it takes... " - @Sara_Mooney— ItsYourGuardianAngel (@SirtuinOne) June 27, 2014
http://t.co/v8umCWwOWs "For Christ’s love compels us, because we are convinced that one died for all, and therefore all died." -2co5.14.niv— ItsYourGuardianAngel (@SirtuinOne) June 27, 2014
Therefore I said to you that you will die in your sins; for if you do not believe that I am He, you will die in your sins.” John 8:24 #Jesus— Cheong Kok Weng (@ckw09) June 28, 2013
Thursday, June 26, 2014
Why You are Wrong About Death and Aging. http://t.co/tK0WKPLePV— Aging Research News (@AGE) June 26, 2014
Khannea Suntzu • • Jun 26, 2014
The clock is ticking.
Aubrey was just there at the cusp of the new millennium to emphasize the point that conceivably someone can do this. He was the first to make this point in a particularly emphatic, plausible, rational manner. Any number of similarly talented, motivated, resourced people could have taken up this gauntlet. Aubrey was the first to do so, and there will be statues made of him for doing so.
Even if he dies from aging before His time.
And now he has taken up this challenge, millions will in fact take up this challenge in his footsteps. Aubrey de Grey will therefore be contemplated. This video will be reviewed for millenia.
Now we see the challenge clearly before us, and the clock has start ticking. Solving aging and reverse engineering youth is not an infinitely complex challenge. It may be a challenge that takes 20 years, or it may be a challenge that takes 200 years. It won't be a challenge that takes 500 years.
That means, in all likelihood, somewhere this century there will be a person living well beyond a natural lifespan. In all likelihood it means that in a conceivably or inconceivably short (depending on your opinion) timespan, someone somewhere will implement treatments. These may initially be modest, expensive, painful or flawed treatments.
But pretty soon this will be a reality. And when it is, it will never go away again.
Many people might not like the idea, but that's just the way it is. They'll have to wrap their heads around it. They will just have to come to terms with this new outlandish motion.
Yesterday we were shackled to the ground and suddenly we can fly. A few decades later millions routinely fly. Yesterday people were imprisoned on the planet and now people can go to the moon.
Things change, and we adapt. The more things change the more they'll never be the same again.
The problem of life extension and rejuvenation in the long run isn't a problem of research grants or entropy or time or insurmountable laboratory odds. It is a matter of imagination. It is a matter of psychotherapy.
And that's the role the interviewer took - he played the unimaginative person. The interlocutor. The skeptic. The contemporary. The simplicius.
History will be shocked at this hesitancy, and one day it will be hard to understand this point of view. The future will say "what were these people thinking?"
The sooner the better.
Sunday, June 22, 2014
NEW Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation http://t.co/5ctKfJjY6k— Wiley Genetics (@WileyGenetics) April 23, 2013
Metformin lowers the threshold for stress-induced senescence: a role for the microRNA-200 family and miR-205.http://t.co/hDs4p28T— anamika mehta (@anamika13) October 3, 2012
Tuesday, June 17, 2014
Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. http://t.co/NpCeFcrZCC— Kelly A. Hogan Ph.D. (@Loose_Lab_Rat) June 17, 2014
PPARδ-mediated inhibition of angiotensin II-induced premature senescence in endothelial cells is SIRT1-dependent. http://t.co/pSRZjvBfEs— Kelly A. Hogan Ph.D. (@Loose_Lab_Rat) June 17, 2014
Monday, June 16, 2014
Tuesday, June 10, 2014
Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression.
Tuesday, June 3, 2014
Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway. http://t.co/qSpjlCOm— Remembrane Srl (@alexchat) October 26, 2012
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Go Daphnia! Does genome size matter? this water flea has 8000 more genes than human http://bit.ly/hYpD2H #genome— Juliana A (@Symbiologica) February 4, 2011
In 1900 the average lifespan in the US was 47.— Quirky Facts (@QuirkFacts) February 22, 2015
Regardless whether you put #aging out of your mind or not you're going to continue to age until it becomes a problem. Instead of putting it out of your mind until the problem's at your doorstep why not try to reverse it? Indeed biogerontology & biomedical gerontology are on it.— Zena O'Brien #GeneralStrike (@ZenaMOBrien) January 10, 2019
pic.twitter.com/KHwpVKfIt9— Elsevier Major Reference Works (@ElsevierMRW) December 9, 2019