So AMPK/Sirt1 likely promote each other's activation (which is why teasing out MOA, determining true cause and effect can be hard)— Joshua Samsoondar (@jsamsoondar) July 4, 2018
Further complicating things is timing, duration, dosing, etc. ie in this paper chronic metformin increases murine Sirt1 https://t.co/30vioi25ZF 8/ pic.twitter.com/rufhVQMSXp
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I urge our govt to develop new growth indicators that will give equal importance to non-economic aspects of well-being http://t.co/vI9ch4fE ...